Endocrine Abstracts

Successful implantation requires the synchronisation of viable embryonic development with endometrial receptivity. The mechanisms allowing for the initiation of crosstalk remain elusive, however recent studies have revealed alterations in endometrial microRNAs (miRs) in women suffering repeated implantation failure (RIF). We hypothesised that the IGF1 receptor (IGF1R) is involved in implantation, and that miR145, which is elevated in RIF endometrium and predicted to target IGF...